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  2. JUPITER trial - Wikipedia

    en.wikipedia.org/wiki/JUPITER_trial

    JUPITER was a randomized double-blind placebo-controlled study investigating the use of rosuvastatin in the primary prevention of cardiovascular disease.The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP).

  3. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    The dose-related magnitude of rosuvastatin on blood lipids was determined in a Cochrane systematic review in 2014. Over the dose range of 1 to 80 mg/day strong linear dose‐related effects were found; total cholesterol was reduced by 22.1% to 44.8%, LDL cholesterol by 31.2% to 61.2%, non-HDL cholesterol by 28.9% to 56.7% and triglycerides by ...

  4. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [5] [65] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke, and 5 cases of muscle damage per 10,000 people treated. [34]

  5. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...

  6. Words are overrated. Here’s why we’re addicted to ‘silent ...

    www.aol.com/words-overrated-why-addicted-silent...

    This practice can also be used by showing people silent reviews and having them interpret the message the creator is trying to convey, making them a great teaching tool, according to Paul.

  7. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    In a 2017 scientific review, researchers found that L-citrulline supplementation may increase nitric oxide levels, reduce blood pressure and improve flow to blood vessels.

  8. Statin-associated autoimmune myopathy - Wikipedia

    en.wikipedia.org/wiki/Statin-associated...

    SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.

  9. Menendez brothers aren't a package deal, could face ... - AOL

    www.aol.com/news/menendez-brothers-arent-package...

    L.A. County Dist. Atty. Nathan Hochman says he will not consider Erik and Lyle Menendez a package deal when it comes to making a decision on possible resentencing.

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