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The LD50 (oral, rats) is 756 mg/kg. Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday.
Trichlorobenzene (TCB) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C 6 H 3 Cl 3. They differ by the positions of the chlorine atoms around the ring: 1,2,3-Trichlorobenzene; 1,2,4-Trichlorobenzene; 1,3,5-Trichlorobenzene
1,2,3-Trichlorobenzene is an organochlorine compound with the chemical formula C 6 H 3 Cl 3. [ 1 ] [ 2 ] This is one of three isomers of trichlorobenzene ; the two others are 1,2,4-Trichlorobenzene and 1,3,5-Trichlorobenzene .
They have the formula C 6 H 6–n Cl n, where n = 1–6 is the number of chlorine atoms. Depending on the number of chlorine substituents, there may be several constitutional isomers possible. Monochlorobenzene; Dichlorobenzene. 1,2-Dichlorobenzene; 1,3-Dichlorobenzene; 1,4-Dichlorobenzene; Trichlorobenzene. 1,2,3-Trichlorobenzene; 1,2,4 ...
ArSO 2 Cl → ArCl + SO 2. 1,2,4-Trichlorobenzene is made industrially in this way. Treatment of alkanesulfonyl chlorides having α-hydrogens with amine bases can give sulfenes, highly unstable species that can be trapped: RCH 2 SO 2 Cl → RCH=SO 2 + HCl. Reduction with tetrathiotungstate ions (WS 2− 4) induces dimerization to the disulfide ...
1,2,4-Trichlorobenzene; 1,3,5-Trichlorobenzene This page was last edited on 31 January 2024, at 19:46 (UTC). Text is available under the Creative Commons ...
1,2,4,5-tetrachlorobenzene once was used as intermediates in the production of pesicides, [3] specifically trichlorophenols. This method has been discontinued because it also produced 2,3,7,8-tetrachlorodibenzo-p- dioxin .
The 1,3- isomer is uncommon because it is a meta- compound, while chlorine, like all halogens, is an ortho/para-director in terms of electrophilic aromatic substitution. It is mainly used as a precursor to 1,2-dichloro-4-nitrobenzene, an intermediate in the synthesis of agrochemicals. [5] In terms of niche applications, 1,2-dichlorobenzene is a ...