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Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
ExtenZe packaging . ExtenZe is an herbal nutritional supplement claiming to promote "natural male enhancement", a euphemism for penis enlargement. [1] ExtenZe paid $6 million to settle a class-action false advertising lawsuit in 2010. [2] Websites selling the product make several more detailed claims, including acquiring a "larger penis".
In the days after UnitedHealthcare CEO Brian Thompson was gunned down in New York City, many social media users took it upon themselves to try to solve the mystery of who killed him — and why.
McColl, S.C. Mayor George Garner II was killed after a collision with another vehicle in the Darlington County town of Mechanicsville, S.C., about 2:40 p.m. on Nov. 26.
If at first — or second, or third — you don't succeed, try, try again. San Francisco's Jake Moody missed three field goals Sunday afternoon against Tampa Bay, but made one that he needed to ...
Nintendo 64 accessories are first-party Nintendo hardware—and third-party hardware, licensed and unlicensed. Nintendo's first-party accessories are mainly transformative system expansions: the 64DD Internet multimedia platform, with a floppy drive, video capture and editor, game building setup, web browser, and online service; the controller plus its own expansions for storage and rumble ...
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