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  2. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Drug interactions are extensive, and are as follows: [13] Azathioprine and 6-mercaptopurine: Azathioprine is metabolised to 6-mercaptopurine which in turn is inactivated by the action of xanthine oxidase - the target of allopurinol. Giving allopurinol with either of these drugs at their normal dose will lead to overdose of either drug; only one ...

  3. Febuxostat - Wikipedia

    en.wikipedia.org/wiki/Febuxostat

    Febuxostat is used to treat chronic gout and hyperuricemia. [12] Febuxostat is typically recommended only for people who cannot tolerate allopurinol. [13] National Institute for Health and Clinical Excellence concluded that febuxostat is more effective than standard doses of allopurinol, but not more effective than higher doses of allopurinol.

  4. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drugdrug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drugdrug interactions. [2] Drug interactions can be of three kinds ...

  5. Probenecid - Wikipedia

    en.wikipedia.org/wiki/Probenecid

    Some of the important clinical interactions of probenecid include those with captopril, indomethacin, ketoprofen, ketorolac, naproxen, cephalosporins, quinolones, penicillins, methotrexate, zidovudine, ganciclovir, lorazepam, and acyclovir. In all these interactions, the excretion of these drugs is reduced due to probenecid, which in turn can ...

  6. Zileuton - Wikipedia

    en.wikipedia.org/wiki/Zileuton

    Zileuton is a weak inhibitor of CYP1A2 [5] and thus has three clinically important drug interactions, which include increasing theophylline, and propranolol levels. It has been shown to lower theophylline clearance significantly, doubling the AUC and prolonging half-life by nearly 25%.

  7. Celebrity Faces Show Alarming Effects Of Ozempic Use As ...

    www.aol.com/hollywood-faces-ozempic-face-crisis...

    Celebrity use and social media promotion of Ozempic have reportedly contributed to a shortage of the drug, which is intended to treat diabetes. “The broad shortage of Ozempic seen currently, ...

  8. Benzbromarone - Wikipedia

    en.wikipedia.org/wiki/Benzbromarone

    Benzbromarone is a uricosuric agent and non-competitive inhibitor of xanthine oxidase [1] used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects.

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