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Shark cartilage is a dietary supplement made from the dried and powdered cartilage of a shark; that is, from the tough material that composes a shark's skeleton. Shark cartilage is marketed under a variety of brand names, including Carticin, Cartilade, or BeneFin, and is marketed explicitly or implicitly as a treatment or preventive for various ...
Lane and Comac further claimed that this was because shark cartilage contained cancer-fighting elements, and so that powdered shark cartilage is an effective treatment for cancer and numerous other conditions. [2] [3] However, there is no scientific evidence that shark cartilage is useful in treating or preventing cancer or any other disease.
Shark cartilage – a dietary supplement made from ground shark skeleton, and promoted as a cancer treatment perhaps because of the mistaken notion that sharks do not get cancer. The Mayo Clinic conducted research and were "unable to demonstrate any suggestion of efficacy for this shark cartilage product in patients with advanced cancer". [177]
The effectiveness of glucosamine is controversial. [3] [4] Most recent reviews found it to be equal to [46] [47] or only slightly better than placebo. [10] [48] A difference may exist between glucosamine sulfate and glucosamine hydrochloride, with glucosamine sulfate showing a benefit and glucosamine hydrochloride not. [49]
Glucosamine (C 6 H 13 NO 5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of two polysaccharides, chitosan and chitin. Glucosamine is one of the most abundant monosaccharides. [2]
Chondroitin sulfate is an important structural component of cartilage, [2] and provides much of its resistance to compression. [3] Along with glucosamine, chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis, although large clinical trials failed to demonstrate any symptomatic benefit of chondroitin.
Finally, the 6-O and 3-O positions of GlcNAc moities are sulfated by 6-O (Heparan sulfate 6-O-sulfotransferase) and 3-O (3-OST) sulfotransferases. Chondroitin sulfate and dermatan sulfate, which comprise CSGAGs, are differentiated from each other by the presence of GlcA and IdoA epimers respectively.
Shark liver oil has been misleadingly promoted as a treatment for cancer. In addition, it has been confused with the word "Charcoal" in multiple translations. Despite claims that the alkoxy - glycerols derived from shark liver oil could reduce tumor growth, there is not sufficient evidence to prove this to be a viable treatment option.
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