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A cancer vaccine, or oncovaccine, is a vaccine that either treats existing cancer or prevents development of cancer. [1] Vaccines that treat existing cancer are known as therapeutic cancer vaccines or tumor antigen vaccines. Some of the vaccines are "autologous", being prepared from samples taken from the patient, and are specific to that patient.
[11] [12] [2] [13] [1] Shortly afterward, sipuleucel-T was added to the compendium of cancer treatments published by the National Comprehensive Cancer Network (NCCN) as a "category 1" (highest recommendation) treatment for HRPC. The NCCN Compendium is used by Medicare and major health care insurance providers to decide whether a treatment ...
GVAX is a cancer vaccine composed of whole tumor cells genetically modified to secrete the immune stimulatory cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), and then irradiated to prevent further cell division. The product exists as both autologous (patient specific) and allogeneic (non-patient specific) therapy. [1]
Anti-PD-1 drugs contain not only a Fab region that binds PD-1 but also an Fc region. Experimental work indicates that the Fc portion of cancer immunotherapy drugs can affect the outcome of treatment. For example, anti-PD-1 drugs with Fc regions that bind inhibitory Fc receptors can have decreased therapeutic efficacy. [38]
Personalized mRNA cancer vaccine therapy is a therapy that uses a personalized cancer vaccine based on mRNA vaccine technology to target existing tumors in patients. As of 2024, number of mRNA cancer vaccines are in clinical trials, of which many are personalized therapies based on engineering mRNA-mediated immune response that targets the patient's particular strain of cancer cells.
Fontana, along with 35 others were given an immunotherapy drug alongside the vaccine. Liver cancer is one of the leading causes of cancer deaths worldwide, accounting for over 700,000 deaths each ...
Prof Tureci told Kuenssberg: “What we have developed over decades for cancer vaccine development has been the tailwind for developing the Covid-19 vaccine, and now the Covid-19 vaccine and our ...
Medical gas therapy is a treatment involving the administration of various gases. It has been used in medicine since the use of oxygen therapy. [1] Most of these gases are drugs, including oxygen. [2] Many other gases, collectively known as factitious airs, were explored for medicinal value in the late eighteenth century. In addition to oxygen ...