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  2. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of ...

  3. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/viagra-treats-side-effects-plus...

    Sildenafil’s role as a PDE5 inhibitor might help prevent the thickening of heart muscles, a feature that makes it difficult to pump blood. Viagra has also shown real promise for increasing the ...

  4. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    According to the Food and Drug Administration (FDA), it usually takes 30 to 60 minutes for Viagra or generic sildenafil to start producing a noticeable improvement in your climax quality.

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. Fluconazole - Wikipedia

    en.wikipedia.org/wiki/Fluconazole

    Fluconazole is an antifungal medication used for a number of fungal infections. [5] This includes candidiasis, blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and tinea versicolor. [5]

  8. How Much Viagra Is Too Much? - AOL

    www.aol.com/much-viagra-too-much-105700581.html

    Viagra doses range from 25 to 100 milligrams (mg). A typical starting dose of Viagra or sildenafil dosage is 50 milligrams. ... take a 100-milligram sildenafil dose or a 20-milligram sildenafil ...

  9. Erectile dysfunction - Wikipedia

    en.wikipedia.org/wiki/Erectile_dysfunction

    Erection can be induced by injecting 10–20 μg of prostaglandin E1, with evaluations of the arterial flow every five minutes for 25–30 min (see image). The use of prostaglandin E1 is contraindicated in patients with predisposition to priapism (e.g., those with sickle cell anemia), anatomical deformity of the penis, or penile implants.

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