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Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
Dengue is spread by several species of female mosquitoes of the Aedes genus, principally Aedes aegypti. [1] Infection can be prevented by mosquito elimination and the prevention of bites. [12] Two types of dengue vaccine have been approved and are commercially available.
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
In May 2024, TAK-003 became the second dengue vaccine to be prequalified by the World Health Organization (WHO). [51] This live-attenuated vaccine, developed by Takeda is similar to the Dengvaxia vaccine in the fact that it contains a weakened version of the four variants of dengue virus. The difference between the two vaccines is the TAK-003 ...
A similar initiative is run by Boston Children’s Hospital to track global reports of dengue cases in the media, and researchers in London announced earlier this month the world’s first ...
It is based on a weakened combination of the yellow fever virus and each of the four dengue serotypes. [30] [52] Two studies of a vaccine found it was 60% effective and prevented more than 80 to 90% of severe cases. [53] [54] This is less than wished for by some. [50] There are ongoing programs working on a dengue vaccine to cover all four ...
California last week clocked its fourth case of locally transmitted dengue fever this year — an alarming rise in a sometimes-deadly disease that experts fear could be fueled by climate change.
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