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Pseudoephedrine, sold under the brand name Sudafedamong others, is a sympathomimeticmedicationwhich is used as a decongestantto treat nasal congestion. [1][13][2]It has also been used off-labelfor certain other indications, like treatment of low blood pressure.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness). Intranasal corticosteroids can also be used as decongestants and ...
Each formulation also varies per dose. When purchasing over-the-counter medications, avoid purchasing multiple products with acetaminophen ingredients. The suggested maximum daily intake of acetaminophen is limited to <4 grams (4,000 mg) daily in adults or <2.6g (2,600 mg) daily in children <12 years of age to reduce the risk of liver damage ...
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The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989 by a group led by pharmacologist David Bailey. Their first published clinical report on grapefruit drug interactions was in 1991. [ 9 ] The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used ...
Their effectiveness by themselves in the common cold appears to have a small benefit in adults. [1] Topical decongestants should only be used by patients for a maximum of 5–7 days in a row, because rebound congestion may occur in the form of rhinitis medicamentosa. When used in adults for a short period of time side effects appear to be few.
That was followed by a 2022 recommendation from the U.S. Preventive Services Task Force (USPSTF) stressing that people ages 60 or older should not take a daily baby aspirin for heart health ...
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among numerous others, is a medication used as a decongestant for uncomplicated nasal congestion, [5] used to dilate the pupil, used to increase blood pressure (given intravenously in cases of low blood pressure), and used to relieve hemorrhoids (as a suppository).