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The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose. It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1] The related terms therapeutic window or safety window ...
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication. The list is not exhaustive and not all drugs are used regularly in all countries.
Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range, i.e. drugs that can easily be under- or overdosed. [ 1 ] TDM aimed at improving patient care by individually adjusting the ...
Clonazepam is prescribed for short-term management of epilepsy, anxiety, obsessive–compulsive disorder(OCD), and panic disorderwith or without agoraphobia. [22][23][24] Seizures. [edit] Clonazepam, like other benzodiazepines, while being a first-line treatment for acute seizures, is not suitable for the long-term treatment of seizures due to ...
While a 2018 study found that the 21 most commonly prescribed antidepressant medications were slightly more effective than placebos for the short-term (acute) treatments of adults with major depressive disorder, [19] [20] other research has found that the placebo effect may account for most or all of the drugs' observed efficacy.
Trazodone, sold under many brand names, [ 1 ] is an antidepressant medication, [ 20 ] used to treat major depressive disorder, anxiety disorders, and insomnia. [ 20 ] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class. [ 21 ][ 22 ] The medication is taken orally.
Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [ 11 ] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [ 92 ]
Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [10] The effectiveness of sertraline for depression is similar to that of other antidepressants, and the differences are mostly confined to side effects. Sertraline is better tolerated than the older ...