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Zolmitriptan, sold under the brand name Zomig among others, is a triptan used in the acute treatment of migraine attacks with or without aura and cluster headaches. It is a selective serotonin receptor agonist of the 1B and 1D subtypes. It was patented in 1990 and approved for medical use in 1997. [ 2]
The triptan drug class includes 1st generation sumatriptan (which has poor bioavailability), and second generation zolmitriptan. [2] Due to their safety, efficacy and selectivity, triptans are considered first line agents for abortion of migraines. [2] These medications are selective 5-HT 1B/1D receptor agonists with some activity at 5-HT 1F.
Management of migraine. Migraine may be treated either prophylactically (preventive) or abortively (rescue) for acute attacks. [ 1] Migraine is an complex condition; there are various preventive treatments which disrupt different links in the chain of events that occur during a migraine attack. Rescue treatments also target and disrupt ...
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Here, experts talk about what people often misunderstand about migraines. 1. Migraine attacks aren't the same thing as a headache. Migraine attacks are not just a simple headache, experts say ...
Sumatriptan, sold under the brand name Imitrex among others, is a medication used to treat migraine headaches and cluster headaches. [ 1] It is taken orally, intranasally, or by subcutaneous injection. [ 2] Therapeutic effects generally occur within three hours.
A drug used in the prevention of migraine may also help reduce so-called rebound headaches, according to a new review of data from a randomized, double-blind, placebo-controlled migraine trial.
Atogepant, sold under the brand name Qulipta among others, is a medication used to prevent migraines. [ 4][ 5] It is a gepant, an orally active calcitonin gene-related peptide receptor antagonist. [ 4][ 7] The most common side effects include nausea, constipation, tiredness, somnolence (sleepiness), decreased appetite, and decreased weight.