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The BNF for Children developed from the British National Formulary (BNF), which prior to 2005 had provided information on the treatment of children, with the doses largely determined by calculations based on the body weight of the child. The guidance was provided by pharmacists and doctors whose expertise was in the care of adults.
Aztreonam/avibactam, sold under the brand name Emblaveo, is a fixed-dose combination antibacterial medication used for the treatment of aerobic Gram-negative infections. [4] It is a combination of aztreonam , a monobactam antibacterial; and avibactam , a beta-lactamase inhibitor . [ 4 ]
Aztreonam inhibits cell wall synthesis by blocking peptidoglycan crosslinking to cause bacterial death. [2] Aztreonam was approved for medical use in the United States in 1986. [2] It was removed from the World Health Organization's List of Essential Medicines in 2019. [4] [5] It is available as a generic medication. [2]
Aztreonam is the archetypal monobactam. [6] Other monobactams include tigemonam , [ 7 ] nocardicin A , carumonam and tabtoxin . An example of a monobactam that lacks antibiotic activity, but is used clinically for other purposes, is the cholesterol absorption inhibitor ezetimibe which is used to treat hypercholesterolemia .
The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
Weight loss injections are safe and effective when used as prescribed. GLP-1s are usually prescribed alongside a healthy diet and frequent exercise. GLP-1s are usually prescribed alongside a ...
FRANKFURT (Reuters) -Eli Lilly said on Thursday it would bring the Mounjaro drug against obesity and diabetes to British patients within weeks after winning clearance for pre-filling it into an ...
Backbone structure of a carbapenem. Carbapenems are a class of very effective antibiotic agents most commonly used for treatment of severe bacterial infections.This class of antibiotics is usually reserved for known or suspected multidrug-resistant (MDR) bacterial infections.