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Pericytes and renal mesangial cells are some examples of modified myofibroblast-like cells. Myofibroblasts may interfere with the propagation of electrical signals [5] controlling heart rhythm, [6] leading to arrhythmia in both patients who have suffered a heart attack and in foetuses. Ursodiol is a promising drug for this condition. [7]
Parietal epithelial cell (PEC) Podocyte; Angioblast → Endothelial cell; Mesangial cell. Intraglomerular; Extraglomerular; Juxtaglomerular cell; Macula densa cell; Stromal cell → Interstitial cell → Telocytes; Kidney proximal tubule brush border cell; Kidney distal tubule cell; Connecting tubule cells; α-intercalated cell; β-intercalated ...
Histopathologically, FMTs consist of neoplastic connective tissue cells which have differented into cells that have microscopic appearances resembling fibroblasts and/or myofibroblasts. The fibroblastic cells are characterized as spindle-shaped cells with inconspicuous nucleoli that express vimentin , an intracellular protein typically found in ...
These cells create a stromal niche for cancer cells and especially cancer stem cells, where they employ both paracrine and direct cell-contact to maintain stemness in cancer stem cells. In turn, this enables these cancer stem cells to escape chemotherapy and radiotherapy, while the cancer-associated fibroblasts also create an environment that ...
Pancreatic stellate cells (PaSCs) are classified as myofibroblast-like cells that are located in exocrine regions of the pancreas. [ 1 ] [ 2 ] PaSCs are mediated by paracrine and autocrine stimuli and share similarities with the hepatic stellate cell . [ 2 ]
Concerns have grown since the National Institutes of Health published a study in May finding that, on average, 91 brain samples contained roughly 10 to 20 times more than other organs (e.g., the ...
Meningeal cells are specialized fibroblast-like cells that surround the CNS and major blood vessels. They have been found to co-operate with astrocytes in the initial formation of the glia limitans during development and participate in its continued maintenance throughout life.
Scientists in Brazil found microplastics in the brain tissue of cadavers, according to a new study published Monday in the journal JAMA Network Open.. Mounting research over the last few years has ...