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The subthalamic nucleus (STN) is a small lens-shaped nucleus in the brain where it is, from a functional point of view, part of the basal ganglia system. In terms of anatomy, it is the major part of the subthalamus. As suggested by its name, the subthalamic nucleus is located ventral to the thalamus.
It is a region formed by several grey matter nuclei and their associated white matter structures, namely: [3] The subthalamic nucleus, whose neurons contain glutamate and have excitatory effects over neurons of globus pallidus and substantia nigra; Zona incerta, located between fields of Forel H 1 and H 2.
The subthalamic nucleus is a diencephalic gray matter portion of the basal ganglia, and the only portion of the ganglia that produces an excitatory neurotransmitter, glutamate. The role of the subthalamic nucleus is to stimulate the SNr-GPi complex and it is part of the indirect pathway. The subthalamic nucleus receives inhibitory input from ...
The mesencephalic locomotor region (MLR) is a functionally defined area of the midbrain that is associated with the initiation and control of locomotor movements in vertebrate species. [ 1 ] [ 2 ] Neuroanatomical organization
Subthalamic nucleus cells can then send more activating signals to some parts of the globus pallidus internus and substantia nigra pars reticulata. Thus, parts of these two nuclei are driven to send more inhibitory signals to the ventrolateral nucleus of the thalamus, which prevents the development of significant activity in the motor cerebral ...
Indirect and direct pathways.Some neuroanatomy is excluded for simplicity.. The two major input structures of the circuit are the striatum and the subthalamic nucleus (STN). The striatum receives inputs from both the cortex and the pars compacta of the substantia nigra (SNc), while the STN only receives cortical inputs.
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Pontine nuclei; Pontine cranial nerve nuclei. Chief or pontine nucleus of the trigeminal nerve sensory nucleus (V); Motor nucleus for the trigeminal nerve (V); Abducens nucleus (VI) ...