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In anatomy, the interstitium is a contiguous fluid-filled space existing between a structural barrier, such as a cell membrane or the skin, and internal structures, such as organs, including muscles and the circulatory system.
The interstitium of the kidney increases in osmolarity outside as the loop of Henle descends from 600 mOsm/L in the outer medulla of the kidney to 1200 mOsm/L in the inner medulla. The descending portion of the loop of Henle is extremely permeable to water and is less permeable to ions, therefore water is easily reabsorbed here and solutes are ...
Extracellular fluid may be mechanically guided in this circulation by the vesicles between other structures. Collectively this forms the interstitium, which may be considered a newly identified biological structure in the body. [36] However, there is some debate over whether the interstitium is an organ. [37]
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Claude Bernard, French physician who introduced the concept of homeostasis. The human body and even its individual body fluids may be conceptually divided into various fluid compartments, which, although not literally anatomic compartments, do represent a real division in terms of how portions of the body's water, solutes, and suspended elements are segregated.
They are found in less than half of all Leydig cell tumors, but when present, they may serve to confirm the diagnosis of a Leydig cell tumor. [ 10 ] [ 11 ] No other interstitial cell within the testes has a nucleus or cytoplasm with these characteristics, making identification relatively easy.
The medullary interstitium is the tissue surrounding the loop of Henle in the medulla. It functions in renal water reabsorption by building up a high hypertonicity , which draws water out of the thin descending limb of the loop of Henle and the collecting duct system .
The thick ascending limb is found in the medulla of the kidney, and the thick ascending limb can be divided into a part that is in the renal medulla and a part that is in the renal cortex. The ascending limb is much thicker than the descending limb.