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  2. Neurobiological effects of physical exercise - Wikipedia

    en.wikipedia.org/wiki/Neurobiological_effects_of...

    [50] [54] [55] Physical activity is associated with increased levels of IGF-1 in blood serum, which is known to contribute to neuroplasticity in the brain due to its capacity to cross the blood–brain barrier and blood–cerebrospinal fluid barrier; [5] [50] [53] [54] consequently, one review noted that IGF-1 is a key mediator of exercise ...

  3. Afterhyperpolarization - Wikipedia

    en.wikipedia.org/wiki/Afterhyperpolarization

    Afterhyperpolarization, or AHP, is the hyperpolarizing phase of a neuron's action potential where the cell's membrane potential falls below the normal resting potential. This is also commonly referred to as an action potential's undershoot phase. AHPs have been segregated into "fast", "medium", and "slow" components that appear to have distinct ...

  4. Neural accommodation - Wikipedia

    en.wikipedia.org/wiki/Neural_accommodation

    During neuronal accommodation, the slowly rising depolarisation drives the activation and inactivation, as well as the potassium gates simultaneously and never evokes action potential. Failure to evoke action potential by ramp depolarisation of any strength had been a great puzzle until Hodgkin and Huxley created their physical model of action ...

  5. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    The currents flowing in due to an action potential spread out in both directions along the axon. [52] However, only the unfired part of the axon can respond with an action potential; the part that has just fired is unresponsive until the action potential is safely out of range and cannot restimulate that part.

  6. Biological neuron model - Wikipedia

    en.wikipedia.org/wiki/Biological_neuron_model

    The signal is a short electrical pulse called action potential or 'spike'. Fig 2. Time course of neuronal action potential ("spike"). Note that the amplitude and the exact shape of the action potential can vary according to the exact experimental technique used for acquiring the signal.

  7. Compound action potential - Wikipedia

    en.wikipedia.org/wiki/Compound_action_potential

    Alike individual action potentials, CAP waveforms are typically biphasic presenting a negative and positive peak. The morphological attributes of the CAP (amplitude, spread, latency) depend on various factors including electrode placement, stimulus intensity, number of fibers recruited, the synchronization of action potentials, and conduction ...

  8. Soliton model in neuroscience - Wikipedia

    en.wikipedia.org/wiki/Soliton_model_in_neuroscience

    Persistence of action potential over wide temperature range An important assumption of the soliton model is the presence of a phase transition near the ambient temperature of the axon ("Formalism", above). Then, rapid change of temperature away from the phase transition temperature would necessarily cause large changes in the action potential.

  9. Low-threshold spikes - Wikipedia

    en.wikipedia.org/wiki/Low-threshold_spikes

    LTS result in the neuron reaching the threshold for an action potential. LTS is a large depolarization due to an increase in Ca 2+ conductance, so LTS is mediated by calcium (Ca 2+ ) conductance. The spike is typically crowned by a burst of two to seven action potentials, which is known as a low-threshold burst.

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