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Bobbitt was born on January 18, 1930, in Charleston, West Virginia, to parents James Sterling Bobbitt and Grace McCue Bobbitt. [1] He earned a Bachelor of Science degree in chemistry from West Virginia University in 1951 and a PhD from Ohio State University in 1955, working with Melville L. Wolfrom on periodate oxidations.
Carbohydrate Research is a peer-reviewed scientific journal covering research on the chemistry of carbohydrates. It is published by Elsevier and was established in 1965. The editor-in-chief is M. Carmen Galan (University of Bristol). According to the Journal Citation Reports, the journal has a 2022 impact factor of 3.1. [1]
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Carbohydrate synthesis is a sub-field of organic chemistry concerned with generating complex carbohydrate structures from simple units (monosaccharides). The generation of carbohydrate structures usually involves linking monosaccharides or oligosaccharides through glycosidic bonds, a process called glycosylation .
Carbohydrates (literally hydrates of carbon) are chemical compounds, which together with proteins, lipids , and nucleic acids (RNA/DNA), constitute the 4 principal biological macromolecules of which all life on Earth is composed.
The Wohl degradation in carbohydrate chemistry is a chain contraction method for aldoses. [1] The classic example is the conversion of glucose to arabinose as shown below. The reaction is named after the German chemist Alfred Wohl (1863–1939).
The typical ranges of specific carbohydrate carbon chemical shifts in the unsubstituted monosaccharides are: Anomeric carbons: 90-100 ppm; Sugar ring carbons bearing a hydroxy function: 68-77; Open-form sugar carbons bearing a hydroxy function: 71-75; Sugar ring carbons bearing an amino function: 50-56; Exocyclic hydroxymethyl groups: 60-64