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At times, if a seizure specifically affects the hippocampus, the individual afflicted can encode memory; however, that memory rapidly extinguishes. [8] Accompanying the onset of epilepsies is hippocampal sclerosis, also known as Ammon's horn sclerosis. Individuals afflicted suffer unilateral volume loss, as evidenced by MRI scans. [9]
Resting state fMRI (rs-fMRI or R-fMRI), also referred to as task-independent fMRI or task-free fMRI, is a method of functional magnetic resonance imaging (fMRI) that is used in brain mapping to evaluate regional interactions that occur in a resting or task-negative state, when an explicit task is not being performed.
Hippocampal sclerosis (HS) or mesial temporal sclerosis (MTS) is a neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus. [1] Neuroimaging tests such as magnetic resonance imaging (MRI) and positron emission tomography (PET) may identify individuals with hippocampal sclerosis. [ 2 ]
MRI scans showing hyperintensities. A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss.
Amygdalohippocampectomy is a surgical procedure for the treatment of epilepsy.It consists of the removal of the hippocampus, which has a role in memory, spatial awareness, and navigation, [1] and the amygdalae, which have a role in the processing and memory of emotional reactions, [2] both structures forming part of the limbic system of the brain.
Recovery after ATL can take several weeks to months. Anti-seizure medications will be continued for several months after ATL. As it is an open surgery it takes time for the brain to heal. [10] Speech therapy, occupational therapy, etc. can help recovery. About 90% of people experience an improvement in seizures after temporal lobectomy.
Voxel-based morphometry is a computational approach to neuroanatomy that measures differences in local concentrations of brain tissue, through a voxel-wise comparison of multiple brain images. [ 1 ] [ 2 ] In traditional morphometry , volume of the whole brain or its subparts is measured by drawing regions of interest (ROIs) on images from brain ...
Reduced hippocampal neurogenesis leads to a reduction in hippocampal volume. A genetically smaller hippocampus has been linked to a reduced ability to process psychological trauma and external stress, and subsequent predisposition to psychological illness. [126] Depression without familial risk or childhood trauma has been linked to a normal ...