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[11] [28] Compared to placebo, beta-blockers have a greater benefit in stroke reduction, but no difference on coronary heart disease or all-cause mortality. [32] However, three-quarters of active beta-blocker treatments in the randomised controlled trials included in the review used atenolol, and none used the newer vasodilating beta-blockers. [33]
Without proper treatment, hypertension can lead to: ... Men have a higher risk of high blood pressure than women in middle age, but women have a higher risk than men in older age. ... Beta-blockers.
For the treatment of primary hypertension (high blood pressure), meta-analyses of studies which mostly used atenolol have shown that although beta blockers are more effective than placebo in preventing stroke and total cardiovascular events, they are not as effective as diuretics, medications inhibiting the renin–angiotensin system (e.g., ACE ...
In particular, beta-blockers are no longer recommended as first-line treatment due to relative adverse risk of stroke and new-onset of type 2 diabetes when compared to other medications, [3] while certain specific beta-blockers such as atenolol appear to be less useful in overall treatment of hypertension than several other agents. [36]
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
Beta blockers are medications that often prevent paroxysmal and labile hypertension as they interact with the sympathetic nervous system. Beta blockers help reduce blood pressure by blocking the effects of hormone epinephrine, also known as adrenaline. The effect of taking beta blockers can help lower the heart rate as well as help improve the ...
Atenolol is a beta blocker medication primarily used to treat high blood pressure and heart-associated chest pain. [7] Although used to treat high blood pressure, it does not seem to improve mortality in those with the condition. [8] [9] Other uses include the prevention of migraines and treatment of certain irregular heart beats.
While once a first-line treatment for hypertension, the role of beta blockers was downgraded in June 2006 in the United Kingdom to fourth-line, as they do not perform as well as other drugs, particularly in the elderly, and evidence is increasing that the most frequently used beta blockers at usual doses carry an unacceptable risk of provoking ...
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