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Depending on the type of allergen causing it, the rash can ooze, drain or crust and it can become raw, scaled or thickened. Also, it is possible that the skin lesion does not take the form of a rash but it may include papules, blisters, vesicles or even a simple red area. The main difference between the rash caused by allergic contact ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
The rash appears immediately in irritant contact dermatitis; in allergic contact dermatitis, the rash sometimes does not appear until 24–72 hours after exposure to the allergen. Blisters or wheals: Blisters , wheals (welts), and urticaria (hives) often form in a pattern where skin was directly exposed to the allergen or irritant.
Maculopapular rash; Petechia or edema; Hyperprolactinaemia [Note 5] Impaired thermoregulation [Note 6] Hyperglycaemia [Note 7] Other hypothalamic abnormalities [Note 8] Blurred vision; Confusion; Raised ANA titre; Positive SLE cells; Mydriasis [Note 9] Atonic colon; Seizure [Note 10] Agitation (restlessness)
These are called "simple" drug eruptions. However, more serious drug eruptions may be associated with organ injury such as liver or kidney damage and are categorized as "complex". [2] Drugs can also cause hair and nail changes, affect the mucous membranes, or cause itching without outward skin changes. [3]
The second step is immune complex deposition, during which the complexes leave the plasma and are deposited into tissues. Finally, the third step is the inflammatory reaction, during which the classical pathway is activated and macrophages and neutrophils are recruited to the affected tissues. Such reactions may progress to immune complex diseases.
Hives, or urticaria, is a form of skin rash with red, raised, itchy bumps. [1] They may also burn or sting. [2] Hives can appear anywhere on the surface of the skin. Whether the trigger is allergic or not, a complex release of inflammatory mediators, including histamine from cutaneous mast cells, results in fluid leakage from superficial blood ...
Symptoms often include a rash, joint pain, fever, and lymphadenopathy. It is a type of hypersensitivity, specifically immune complex hypersensitivity . The term serum sickness–like reaction (SSLR) is occasionally used to refer to similar illnesses that arise from the introduction of certain non-protein substances, such as penicillin. [1]
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