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In follow-up research at the ICR in 1964, Professors Peter Brookes and Philip Lawley proved that chemical carcinogens act by damaging DNA, leading to mutations and the formation of tumours, proving that cancer is a genetic disease based on mutational events. [7] In 1954 the institute was officially renamed The Institute of Cancer Research (ICR).
It covers research on all aspects of cancer and cancer-related biomedical sciences and was established in 1941. The editor-in-chief is Chi Van Dang. [1] The journal was established in 1916 as the Journal of Cancer Research, was renamed American Journal of Cancer in 1931, and obtained its current name in 1941.
The Immunologic Constant of Rejection (ICR), is a notion introduced by biologists to group a shared set of genes expressed in tissue destructive-pathogenic conditions like cancer and infection, along a diverse set of physiological circumstances of tissue damage or organ failure, including autoimmune disease or allograft rejection. [1]
Sir Melvyn Francis Greaves (born 12 September 1941) is a British cancer biologist, and Professor of Cell Biology at the Institute of Cancer Research (ICR) in London. [1] He is noted for his research into childhood leukaemia and the roles of evolution in cancer, including important discoveries in the genetics and molecular biology underpinning leukaemia.
Jonathon Noë Joseph Pines (born 11 October 1961 [4]) is Head of the Cancer Biology Division at the Institute of Cancer Research in London. He was formerly a senior group leader at the Gurdon Institute at the University of Cambridge .
In 2023, she joined the Institute of Cancer Research as Professor of Cancer Cell and Metastasis Biology. She leads the Cytoskeleton and Cancer Metastasis Team. In 2014, Sanz-Moreno joined Cancer Research UK's Women of Influence initiative helping provide personal and career development support for female cancer research scientists.
The Royal Marsden works in collaboration with The Institute of Cancer Research (ICR), [4] which was founded in 1909 as the hospital's research department. [5] The ICR legally separated from the hospital when the latter became part of the NHS in 1948, [6] but the two retained close ties.
Cancer Discovery has become a premier journal in the field of cancer research, with a 2020 impact factor of 39.397 that is the highest among the AACR journals. [6] [7] Research published in the journal includes identification of actionable genomic alterations in cancer, mechanisms of therapy resistance, clinical trials on targeted therapy, and ...