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Secukinumab, sold under the brand name Cosentyx among others, is a human IgG1κ monoclonal antibody used for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. [ 4 ] [ 5 ] [ 6 ] It binds to the protein interleukin (IL)-17A and is marketed by Novartis .
"Salicylic acid is a topical medication used to treat acne and a variety of other skin conditions, like warts and psoriasis," says double-board-certified dermatologist, Maya Thosani, MD. While it ...
Salicylic acid is used as a medicine to help remove the outer layer of the skin. [1] As such it is used to treat warts, skin tags, calluses, psoriasis, dandruff, acne, ringworm, and ichthyosis. [1] [2] For conditions other than warts, it is often used together with other medications. [2] It is applied to the area affected. [1]
The FDA approves Novartis' (NVS) Cosentyx for the treatment of children and adolescents with enthesitis-related arthritis and psoriatic arthritis.
The medication was approved by the US Food and Drug Administration (FDA) for the treatment of acne in August 2020. [10] The FDA approved clascoterone based on evidence from two clinical trials (Trial 1/NCT02608450 and Trial 2/NCT02608476) of 1,440 participants 9 to 58 years of age with acne vulgaris. [20]
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Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity. [2] It was developed by Merck Sharp & Dohme in 1971, as MK647, after showing promise in a research project studying more potent chemical analogs of aspirin. [3]
The therapeutic effects of salicylic acids were first documented in 1763 by Edward Stone, with acetylsalicylic acid being synthesized by Felix Hoffmann, a chemist working under Bayer, in 1897. [4] Acetylsalicylic acid-derived salt compounds were first discovered in 1970, [5] and the synthesis of lysine acetylsalicylate was first documented in ...