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2. Huntington's disease - Wikipedia

   en.wikipedia.org/wiki/Huntington's_disease

   The area of the brain most damaged in early Huntington's disease is the dorsal striatum made up of the caudate nucleus and the putamen. Initially, damage to the brain is regionally specific with the dorsal striatum in the subcortical basal ganglia being primarily affected, followed later by cortical involvement in all areas.

3. Huntingtin - Wikipedia

   en.wikipedia.org/wiki/Huntingtin

   Huntingtin (Htt) is the protein coded for in humans by the HTT gene, also known as the IT15 ("interesting transcript 15") gene. [5] Mutated HTT is the cause of Huntington's disease (HD), and has been investigated for this role and also for its involvement in long-term memory storage.

4. Neurodegenerative disease - Wikipedia

   en.wikipedia.org/wiki/Neurodegenerative_disease

   Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. [4]

5. Subcortical dementia - Wikipedia

   en.wikipedia.org/wiki/Subcortical_dementia

   Subcortical dementias includes those diseases which predominantly affects the basal ganglia along with features of cognitive decline.. Diseases such as progressive supranuclear palsy, Huntington's chorea and Parkinson's disease are different in many features from the other cortical dementias like Alzheimer's disease.

6. Huntington's disease-like syndrome - Wikipedia

   en.wikipedia.org/wiki/Huntington's_disease-like...

   Huntington's disease-like syndromes (HD-like syndromes, or HDL syndromes) are a family of inherited neurodegenerative diseases that closely resemble Huntington's disease (HD) in that they typically produce a combination of chorea, cognitive decline or dementia and behavioural or psychiatric problems.

7. Cognitive disorder - Wikipedia

   en.wikipedia.org/wiki/Cognitive_disorder

   Although Alzheimer's disease accounts for the majority of cases of neurocognitive disorders, there are various medical conditions that affect mental functions such as memory, thinking, and the ability to reason, including frontotemporal degeneration, Huntington's disease, dementia with Lewy bodies, traumatic brain injury (TBI), Parkinson's ...