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Mucuna pruriens is a tropical legume native to Africa and tropical Asia and widely naturalized and cultivated. [2] Its English common names include monkey tamarind , velvet bean , Bengal velvet bean , Florida velvet bean , Mauritius velvet bean , Yokohama velvet bean , cowage , cowitch , lacuna bean , and Lyon bean . [ 2 ]
Bufotenin has been identified as a component in the latex of the takini (Brosimum acutifolium) tree, which is used as a psychedelic by South American shamans, [35] and in the seeds of Mucuna pruriens. [36] Bufotenin has also been identified in Amanita muscaria, Amanita citrina, A. porphyria, and A. tomentella. [37] [38]
Itching powder was created from Mucuna pruriens in the early-19th century as a cure for lost feeling in the epidermis. When a person would lose feeling on their skin in conditions such as paralysis, the powder (mixed with lard to form an ointment) was used as a local stimulant believed to treat the condition. [9] [10]
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L-DOPA is used medically under the name levodopa in the treatment of Parkinson's disease and certain other medical conditions. It is usually used in combination with a peripherally selective aromatic L-amino acid decarboxylase (AAAD) inhibitor such as carbidopa or benserazide. These agents increase the strength and duration of levodopa.
M. pruriens may also contain chemicals such as serotonin, 5-HTP, nicotine, and the hallucinogenic tryptamines 5-MeO-DMT, bufotenine and dimethyltryptamine, [7] [8] [verification needed] Mucuna is not traditionally consumed as a food crop, but some preliminary experiments have shown that if the antinutrients are removed or at least brought down ...
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