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Peripheral blood smear in patient with thrombotic thrombocytopenic purpura. Typical schistocytes are annotated. A schistocyte or schizocyte (from Greek schistos for "divided" and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Schistocytes are typically irregularly shaped, jagged, and have two pointed ends. [1]
The resulting schistocytes (red cell fragments) are also increasingly targeted for destruction by the reticuloendothelial system in the spleen, due to their narrow passage through obstructed vessel lumina.
The kidneys and the central nervous system (brain and spinal cord) are the parts of the body most critically dependent on high blood flow, and are thus the most likely organs to be affected. However, in comparison to TTP, the kidneys tend to be more severely affected in HUS, and the central nervous system is less commonly affected.
Hemangiosarcoma can cause a wide variety of hematologic and hemostatic abnormalities, including anemia, thrombocytopenia [7] (low platelet count), disseminated intravascular coagulation (DIC); presence of nRBC, schistocytes, and acanthocytes in the blood smear; and leukocytosis with neutrophilia, left shift, and monocytosis.
In some cases, a drug can cause the immune system to mistakenly think the body's own red blood cells are dangerous, foreign substances. Antibodies then develop against the red blood cells. The antibodies attach to red blood cells and cause them to break down too early. It is known that more than 150 drugs can cause this type of hemolytic anemia ...
This was obviously a major and closely-watched return for the princess, and body language expert Judi James said she was very much in-sync with Prince William. WPA Pool - Getty Images
What Does Body Positivity Mean in 2022? Robyn Moreno. August 11, 2022 at 5:56 PM. ... But a lot of the language does come from things fat liberationists did in ’70s, and ’80s, especially fat ...
Meaning Origin language and etymology Example(s) dacry(o)-of or pertaining to tears: Greek δάκρυ, tear dacryoadenitis, dacryocystitis-dactyl(o)-of or pertaining to a finger, toe Greek δάκτυλος (dáktulos), finger, toe dactylology, polydactyly: de-from, down, or away from Latin de-dehydrate, demonetize, demotion dent-