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Queen Victoria's sons Edward VII, Alfred, Duke of Saxe-Coburg and Gotha, and Prince Arthur, Duke of Connaught and Strathearn were not haemophiliacs; however, her daughters Alice and Beatrice were confirmed carriers of the gene, and Victoria's son Leopold had haemophilia, making his daughter Princess Alice, Countess of Athlone a carrier as well.
Haemophilia has featured prominently in European royalty and thus is sometimes known as 'the royal disease'. Queen Victoria passed the mutation for haemophilia B [72] [73] to her son Leopold and, through two of her daughters, Alice and Beatrice, to various royals across the continent, including the royal families of Spain, Germany, and Russia.
Victoria (Alexandrina Victoria; 24 May 1819 – 22 January 1901) was Queen of the United Kingdom of Great Britain and Ireland from 20 June 1837 until her death in 1901. Her reign of 63 years and 216 days—which was longer than those of any of her predecessors —constituted the Victorian era .
Prince Leopold, Duke of Albany (Leopold George Duncan Albert; 7 April 1853 – 28 March 1884) was the eighth child and youngest son of Queen Victoria and Prince Albert. Leopold was later created Duke of Albany, Earl of Clarence, and Baron Arklow. He had haemophilia, which contributed to his death following a fall at the age of 30.
Rupert Alexander George Cambridge, Viscount Trematon (24 April 1907 – 15 April 1928) was an English-born great-grandson of Queen Victoria. Originally Prince Rupert of Teck, he and his family relinquished their German titles in 1917.
Alexei inherited haemophilia from his mother Alexandra, an X chromosome hereditary condition that typically affects males, which she had acquired through the line of her maternal grandmother Queen Victoria of the United Kingdom. It was known as the "Royal Disease" because so many descendants of the intermarried European royal families had it ...
She was the third child and second daughter of Queen Victoria of the United Kingdom and Prince Albert of Saxe-Coburg and Gotha. Alice was the first of Queen Victoria's nine children to die, and one of three to predecease their mother, who died in 1901. Her life had been enwrapped in tragedy since her father's death in 1861.
Princess Victoria Eugenie of Battenberg was born on 24 October 1887 at Balmoral Castle, in Scotland.Her father was Prince Henry of Battenberg, the fourth child and third son of Prince Alexander of Hesse and by Rhine and Julia, Princess of Battenberg, and her mother was Princess Beatrice, the fifth daughter of Queen Victoria of the United Kingdom and Prince Albert of Saxe-Coburg and Gotha.