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The 1.06 mm diameter distal tip houses the lens system, which determines the imaging parameters. Prototype systems provide a 70-degree field-of-view and 10-micron resolution. Laser sources are coupled into the single scanning fiber and they use red, green, and blue lasers to create color images.
Two-photon excitation microscopy of mouse intestine.Red: actin.Green: cell nuclei.Blue: mucus of goblet cells.Obtained at 780 nm using a Ti-sapphire laser.. Two-photon excitation microscopy (TPEF or 2PEF) is a fluorescence imaging technique that is particularly well-suited to image scattering living tissue of up to about one millimeter in thickness.
An Er:YAG laser (erbium-doped yttrium aluminium garnet laser, erbium YAG laser) is a solid-state laser whose active laser medium is erbium-doped yttrium aluminium garnet (Er:Y 3 Al 5 O 12). Er:YAG lasers typically emit light with a wavelength of 2940 nm , which is infrared light .
Laser Doppler imaging (LDI) is an imaging method that uses a laser beam to image live tissue. When the laser light reaches the tissue, the moving blood cells generate Doppler components in the reflected (backscattered) light. The light that comes back is detected using a photodiode that converts it into an electrical signal.
Laser radiation being delivered via a fiber for photodynamic therapy to treat cancer. A 40-watt CO 2 laser with applications in ENT, gynecology, dermatology, oral surgery, and podiatry. Laser medicine is the use of lasers in medical diagnosis, treatments, or therapies, such as laser photodynamic therapy, [1] photorejuvenation, and laser surgery.
To achieve the large number of incident photons needed to suppress fluorescence, the laser used to generate the photons must be of a high intensity. Unfortunately, this high intensity laser can lead to the issue of photobleaching the fluorophore. Photobleaching is the name for the destruction of fluorophores by high intensity light.
A fiber laser (or fibre laser in Commonwealth English) is a laser in which the active gain medium is an optical fiber doped with rare-earth elements such as erbium, ytterbium, neodymium, dysprosium, praseodymium, thulium and holmium. They are related to doped fiber amplifiers, which provide light amplification without lasing.
A krypton fluoride laser (KrF laser) is a particular type of excimer laser, [1] which is sometimes (more correctly) called an exciplex laser. With its 248 nanometer wavelength, it is a deep ultraviolet laser which is commonly used in the production of semiconductor integrated circuits , industrial micromachining, and scientific research.
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