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The FDA advises for the risk of birth defects with the use of paroxetine [49] and the MAOI should be avoided. A 2013 systematic review and meta-analysis found that antidepressant use during pregnancy was statistically significantly associated with some pregnancy outcomes, such as gestational age and preterm birth, but not with other outcomes.
[5] [8] It is unclear if use during pregnancy or breastfeeding is safe. [9] Desvenlafaxine was approved for medical use in the United States in 2008. [5] In Europe its application for use was denied in 2009. [6] In 2022, it was the 208th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [10] [11]
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
No antidepressants are FDA approved during pregnancy. [89] Use of antidepressants during pregnancy may result in fetus abnormalities affecting functional development of the brain and behavior. [89] Studies have shown correlations between pregnant women treated with SNRIs and risk of hypertensive disorders, [90] preeclampsia, [91] miscarriage ...
Use during pregnancy and breastfeeding is not generally recommended. [7] It is in the serotonin modulator class of medications and is believed to work both as an SSRI and activator of the 5-HT 1A receptor. [1] Vilazodone was approved for medical use in the United States in 2011 [1] and in Canada in 2018. [8]
While esketamine was in clinical trials and on its way to FDA approval in 2019, so was brexanolone (Zulresso), the first FDA-approved medication specifically for postpartum depression from Sage ...
Taper and conservative switch with a medication-free washout period. Since some tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs) can cause harmful interactions if used ...
The US Food and Drug Administration has approved the medication zuranolone for the treatment of major depressive disorder and severe postpartum depression – making it the first FDA-approved oral ...
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