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About 60% of the metronidazole is metabolized by oxidation to the main metabolite hydroxymetronidazole and a carboxylic acid derivative, and by glucuronidation. The metabolites show antibiotic and antiprotozoal activity in vitro. [61] Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the ...
It is a first-line treatment for amebiasis or giardiasis during pregnancy. [3] Otherwise, it is generally a second line treatment option. [3] It is taken by mouth, applied to the skin, or by injection into a muscle. [3] Common side effects when taken by mouth include loss of appetite, vomiting, abdominal pain, and diarrhea. [3]
During pregnancy, paromomycin is the preferred treatment drug because of its poor intestinal absorption, resulting in less exposure to the foetus. [64] Alternatively, metronidazole can be used after the first trimester as there has been wide experience in its use for trichomonas in pregnancy. [20] [65]
Certain types of vaginitis may result in complications during pregnancy. [1] The three main causes are infections, specifically bacterial vaginosis, vaginal yeast infection, and trichomoniasis. [2] Other causes include allergies to substances such as spermicides or soaps or as a result of low estrogen levels during breast-feeding or after ...
Megan Fox isn’t letting her growing baby bump get in the way of her standout style choices.. The actress, 38, told PEOPLE in an exclusive interview that her personal fashion sense hasn’t ...
Cannabis use during pregnancy should be avoided. [80] There is no known safe dose of cannabis while pregnant and use of cannabis may lead to birth defects, pre-term birth, or low birth weight. [80] Tetrahydrocannabinol (THC), an active ingredient in cannabis, can both cross the placenta and accumulates in high concentrations in breast milk. [81]
A disgraced 93-year-old New Orleans priest pleaded guilty Tuesday to charges involving the sexual assault of a teenage boy in 1975. Lawrence Hecker, who left the ministry in 2002, had been ...
Love Is Blind’s Giannina Gibelli had a hunch she was pregnant with her and Blake Horstmann’s baby before she even took a test. “I pretty much felt implantation, you guys. I am so in tune ...