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Gas gangrene (also known as clostridial myonecrosis [1]) is a bacterial infection that produces tissue gas in gangrene. This deadly form of gangrene usually is caused by Clostridium perfringens bacteria. About 1,000 cases of gas gangrene are reported yearly in the United States. [2] Myonecrosis is a condition of necrotic damage, specific to ...
This toxin has been shown to be the key virulence factor in infection with C. perfringens; the bacterium is unable to cause disease without this toxin. [1] Further, vaccination against the alpha toxin toxoid protects mice against C. perfringens gas gangrene. [2]
Gas gangrene is a bacterial infection that produces gas within tissues. It can be caused by Clostridium, most commonly alpha toxin-producing C. perfringens, or various nonclostridial species. [11] [21] Infection spreads rapidly as the gases produced by the bacteria expand and infiltrate healthy tissue in the vicinity.
Clostridium perfringens is the most common bacterial agent for gas gangrene. [45] Gas gangrene is induced by α-toxin that embeds itself into the plasma membrane of cells and disrupts normal cellular function by altering membrane structure. [8] Some symptoms include blisters, tachycardia, swelling, and jaundice. [45]
More: The mysterious illness affecting dogs is in RI.But do pet owners have to worry? Signs of infection in dogs include a cough that can linger for several weeks, runny eyes and sneezing. The ...
Streptococcus canis is a group G beta-hemolytic species of Streptococcus. [1] It was first isolated in dogs, giving the bacterium its name. These bacteria are characteristically different from Streptococcus dysgalactiae, which is a human-specific group G species that has a different phenotypic chemical composition.
Giardiasis* is an intestinal infection in dogs caused by the protozoa Giardia lamblia. The most common symptom is diarrhea. The zoonotic potential of giardiasis is controversial. [25] [26] Coccidiosis can be caused by a variety of coccidian organisms in dogs, most commonly Isospora. There are usually no symptoms, but diarrhea and weight loss ...
Subcutaneous emphysema is also considered a hallmark of Fournier gangrene. [26] Symptoms of subcutaneous emphysema can result when infectious organisms produce gas by fermentation. When emphysema occurs due to infection, signs that the infection is systemic (i.e. that it has spread beyond the initial location) are also present. [9] [21]
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