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Paneth cells are found throughout the small intestine and the appendix at the base of the intestinal glands. [2] There is an increase in Paneth cell numbers towards the end of the small intestine. [3] Like the other epithelial cell lineages in the small intestine, Paneth cells originate at the stem cell region near the bottom of the gland. [4]
Intestinal glands are found in the epithelia of the small intestine, namely the duodenum, jejunum, and ileum, and in the large intestine (colon), where they are sometimes called colonic crypts. Intestinal glands of the small intestine contain a base of replicating stem cells , Paneth cells of the innate immune system , and goblet cells , which ...
English: Histology of Paneth cells, located at the base of the crypts of the small intestinal mucosa, and displaying merocrine secretion of bright red cytoplasmic granules. H&E stain. - Source for merocrine: Matsubara F (1977). "Morphological study of the Paneth cell. Paneth cells in intestinal metaplasia of the stomach and duodenum of man.".
Paneth cells produce antimicrobial peptides such as human alpha-defensin. [11] [12] Microfold cells (commonly referred to as M cells) sample antigens from the lumen and deliver them to the lymphoid tissue associated with the mucosa (MALT). In the small intestine, M cells are associated with Peyer's patches. Cup cells are a distinct cell type ...
Cell type [2] Location in the mucosa Function Absorptive cell: Epithelium/intestinal glands: Digestion and absorption of nutrients in chyme Goblet cell: Epithelium/intestinal glands: Secretion of mucus Paneth cell: Intestinal glands: Secretion of the bactericidal enzyme lysozyme; phagocytosis G cells: Intestinal glands of duodenum
Paneth cells: small intestine: serous 28 Gley's glands, Sandstroem's glands, parathyroid gland: in the neck parathyroid hormone: 29 Parietal cell: stomach: hydrochloric acid, intrinsic factor: dynamic canaliculi 30 Parotid gland: mouth: saliva tubulo-alveolar 31 Peyer's patches (or glands) ileum, lymphatic glands Pineal gland: brain: melatonin ...
The small intestine or small bowel is an organ in the gastrointestinal tract where most of the absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the pancreatic duct to aid in digestion. The small intestine is about 5.5 metres (18 feet) long and folds ...
Peyer's patches (or aggregated lymphoid nodules) are organized lymphoid follicles, named after the 17th-century Swiss anatomist Johann Conrad Peyer. [1] They are an important part of gut associated lymphoid tissue usually found in humans in the lowest portion of the small intestine, mainly in the distal jejunum and the ileum, but also could be detected in the duodenum.