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The artificial sweetener aspartame has been the subject of several controversies since its initial approval by the U.S. Food and Drug Administration (FDA) in 1974. The FDA approval of aspartame was highly contested, beginning with suspicions of its involvement in brain cancer, [1] alleging that the quality of the initial research supporting its safety was inadequate and flawed, and that ...
On the other hand, while PMID 27606602 *IS* a general review of sweeteners, this peer-reviewed source (which is PLOS One) also goes into detail on the aspartame controversy, on why the peer-reviewed article considers the methodology of the FDA *AND* the EFSA seriously flawed in regards to aspartame, both in how aspartame was originally ...
Aspartame is an artificial non-saccharide sweetener commonly used as a sugar substitute in foods and beverages. [4] 200 times sweeter than sucrose, it is a methyl ester of the aspartic acid/phenylalanine dipeptide with brand names NutraSweet, Equal, and Canderel. [4]
The FDA approved aspartame's use in soft drinks in November 1983, and Pepsi was among the first brands to deploy the product on a large scale in the United States. When G. D. Searle was acquired by Monsanto in 1985, Shapiro moved up the management chain in the ladder, becoming Vice President in 1990, President in 1993 and CEO in 1995.
November 2005 Online publication of Soffritti "First Experimental Demonstration of the Multipotential Carcinogenic Effects of Aspartame Administered in the Feed to Sprague-Dawley Rats" [10] "The results of this mega-experiment indicate that [aspartame] is a multipotential carcinogenic agent, even at a daily dose of 20 mg/kg body weight, much less than the current acceptable daily intake."
This makes aspartame undesirable as a baking sweetener. It is more stable in somewhat acidic conditions, such as in soft drinks. Though it does not have a bitter aftertaste like saccharin, it may not taste exactly like sugar. When eaten, aspartame is metabolized into its original amino acids. Because it is so intensely sweet, relatively little ...
Aspartame was invented by chemists at G. D. Searle & Company in 1965. [2] Searle was bought by Monsanto in 1985. [ 3 ] In March 2000, Monsanto, which was then a subsidiary of the Pharmacia corporation, sold NutraSweet to the private equity firm J.W. Childs Associates . [ 2 ]
[11] As a basis for the damages sought in the lawsuit, the plaintiffs noted that cattle futures dropped 10 percent the day after the episode, and that beef prices fell from 62 cents to 55 cents per pound. [12] Engler's attorneys argued that the rancher lost $6.7 million, and the plaintiffs sought to recoup total losses of more than $12 million ...