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Additional drugs affected by grapefruit juice include, but are not limited to: Some statins, including atorvastatin (Lipitor), [60] lovastatin (Mevacor), and simvastatin (Zocor, Simlup, Simcor, Simvacor) [61] In contrast, pravastatin (Pravachol), [60] fluvastatin (Lescol), and rosuvastatin (Crestor) [61] are unaffected by grapefruit.
Statins to lower cholesterol, such as Lipitor (atorvastatin) and Zocor (simvastatin) Certain antihistamines, like Allegra (fexofenadine) Medications to treat high blood pressure, such as Procardia ...
Still, says Peterson, "most people won't have issues unless they eat large quantities of grapefruit, drink more than one liter per day of grapefruit juice, or consistently eat or drink grapefruit.
Important: If you're taking statins or medications for conditions like high blood pressure, cholesterol, heart arrhythmia, organ transplants, or allergies, it can be dangerous to eat grapefruit.
Furanocoumarins in grapefruit juice (i.e. bergamottin and dihydroxybergamottin) inhibit the cytochrome P450 enzyme CYP3A4, which is involved in the metabolism of most statins (however, it is a major inhibitor of only lovastatin, simvastatin, and to a lesser degree, atorvastatin) and some other medications [130] (flavonoids (i.e. naringin) were ...
The Grapefruit-drug interaction article lists Levothyroxine as one of the drugs whose absorption is affected by grapefruit, but the only readily available research online, which is the one cited, ([1]), concluded that "Grapefruit juice may slightly delay the absorption of levothyroxine, but it seems to have only a minor effect on its ...
There are many adverse effects, interactions and contraindications for antinicotinic and antimuscarinic agents. Adverse effects include hypotension, dry mouth, dry eyes etc. They interact with grapefruit juice and various medications, e.g. warfarin, metoclopramide. Therefore, cautions should be exercised and advice from medical professionals ...
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