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  2. TRH stimulation test - Wikipedia

    en.wikipedia.org/wiki/TRH_stimulation_test

    TRH-stimulation testing however continues to be useful for the differential diagnosis of secondary (pituitary disorder) and tertiary (hypothalamic disorder) hypothyroidism. Patients with these conditions appear to have physiologically inactive TSH in their circulation that is recognized by TSH assays to a degree such that they may yield ...

  3. Combined rapid anterior pituitary evaluation panel - Wikipedia

    en.wikipedia.org/wiki/Combined_rapid_anterior...

    A combined rapid anterior pituitary evaluation panel or triple bolus test or a dynamic pituitary function test is a medical diagnostic procedure used to assess a patient's pituitary function. A triple bolus test is usually ordered and interpreted by endocrinologists. [citation needed] In rare cases, it has been associated with pituitary ...

  4. Thyrotropin-releasing hormone - Wikipedia

    en.wikipedia.org/wiki/Thyrotropin-releasing_hormone

    The hypothalamic-pituitary-thyroid axis. TRH can be seen in green. TRH is synthesized within parvocellular neurons of the paraventricular nucleus of the hypothalamus. [2] It is translated as a 242-amino acid precursor polypeptide that contains 6 copies of the sequence -Gln-His-Pro-Gly-, with both ends of the sequence flanked by Lys-Arg or Arg-Arg sequences.

  5. Thyroid - Wikipedia

    en.wikipedia.org/wiki/Thyroid

    They are however not always accurate, particularly if the cause of hypothyroidism is thought to be related to insufficient thyrotropin releasing hormone (TRH) secretion, in which case it may be low or falsely normal. In such a case a TRH stimulation test, in which TRH is given and TSH levels are measured at 30 and 60-minutes after, may be ...

  6. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    The TRH stimulates the anterior pituitary to produce thyroid-stimulating hormone (TSH). The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH ...

  7. Hypopituitarism - Wikipedia

    en.wikipedia.org/wiki/Hypopituitarism

    Stimulation tests were developed in the 1960s, and in 1973 the triple bolus test was introduced, a test that combined stimulation testing with insulin, GnRH and TRH. [ 31 ] Imaging of the pituitary, and therefore identification of tumors and other structural causes, improved radically with the introduction of computed tomography in the late ...

  8. ACTH stimulation test - Wikipedia

    en.wikipedia.org/wiki/ACTH_stimulation_test

    The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another corticotropic agent such as tetracosactide (cosyntropin, tetracosactrin; Synacthen ...

  9. Evocative/suppression testing - Wikipedia

    en.wikipedia.org/wiki/Evocative/suppression_testing

    Evocative/suppression testing refers to a class of tests performed where one substance is measured both before and after the administration of another substance to determine if the levels are stimulated ("evocative") or suppressed.