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2. Carnitine - Wikipedia

   en.wikipedia.org/wiki/Carnitine

   L-Carnitine, acetyl-l-carnitine, and propionyl-l-carnitine are available in dietary supplement pills or powders, with a daily amount of 0.5 to 1 g considered to be safe. [1] [3] It is also a drug approved by the Food and Drug Administration to treat primary and certain secondary carnitine-deficiency syndromes secondary to inherited diseases. [1 ...

3. Apixaban - Wikipedia

   en.wikipedia.org/wiki/Apixaban

   Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa.

4. L(-)-Carnitine - Wikipedia

   en.wikipedia.org/?title=L(-)-Carnitine&redirect=no

   This page was last edited on 27 September 2013, at 02:54 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

5. Biden targets diabetes drug Jardiance, blood thinner Eliquis ...

   www.aol.com/finance/biden-targets-diabetes-drug...

   Biden targets diabetes drug Jardiance, blood thinner Eliquis, and 8 others for controversial Medicare price talks. But any relief is still years away. Erin Prater. August 29, 2023 at 10:23 AM.

6. Discovery and development of direct Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   Modern direct Xa inhibitors are L-shaped molecules whose ends fit perfectly in the S1 and S4 pockets. The long side of the L-shape has to conform to a highly-specific tunnel within the targets active site. To accomplish that, this part of the molecules is designed to have little formal interactions with FXa in that region.

7. Management of ME/CFS - Wikipedia

   en.wikipedia.org/wiki/Management_of_ME/CFS

   L-Carnitine is an amino acid which includes ALC, a group of natural compounds that have an important role in cellular function. It is required for the transport of fatty acids into the mitochondria during the breakdown of lipids (fats) for the generation of metabolic energy including in muscles and in the brain. [ 69 ]

8. Carnitine biosynthesis - Wikipedia

   en.wikipedia.org/wiki/Carnitine_biosynthesis

   The second step of L-carnitine biosynthesis requires the 3-hydroxy-N ε-trimethyllysine aldolase enzyme. 3-hydroxy-N ε-trimethyllysine aldolase is a pyridoxal phosphate dependent aldolase, and it catalyses the cleavage of 3-hydroxy-N ε-trimethyllysine into 4-N-trimethylaminobutyraldehyde and glycine.

9. Palmitoylcarnitine - Wikipedia

   en.wikipedia.org/wiki/Palmitoylcarnitine

   Palmitoylcarnitine is an ester derivative of carnitine involved in the metabolism of fatty acids.During the tricarboxylic acid cycle (TCA), fatty acids undergo a process known as β-oxidation to produce energy in the form of ATP. β-oxidation occurs primarily within mitochondria, however the mitochondrial membrane prevents the entry of long chain fatty acids (>C10), so the conversion of fatty ...