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In the infant stages of this disease in Europe, many ineffective and dangerous treatments were used. The aim of treatment was to expel the foreign, disease-causing substance from the body, so methods included blood-letting, laxative use, and baths in wine and herbs or olive oil. [67] Mercury was a common, long-standing treatment for syphilis. [68]
The first effective treatment for syphilis was arsphenamine, discovered by Sahachiro Hata in 1909, during a survey of hundreds of newly synthesized organic arsenical compounds led by Paul Ehrlich. It was manufactured and marketed from 1910 under the trade name Salvarsan by Hoechst AG. [113]
In 1906 Ehrlich became the director of the Georg Speyer House in Frankfurt, a private research foundation affiliated with his institute. Here he discovered in 1909 the first drug to be targeted against a specific pathogen: Salvarsan, a treatment for syphilis, which was at that time one of the most lethal and infectious diseases in Europe. In ...
The condition's connection with syphilis was discovered in the late 1880s. Progressively, with the discovery of organic arsenicals such as Salvarsan and Neosalvarsan (1910s), the development of pyrotherapy (1920s), and the widespread availability and use of penicillin in the treatment of syphilis (1940s), the condition was rendered avoidable ...
Salvarsan treatment kit for syphilis, Germany, 1909–1912 [5] Arsphenamine was first synthesized in 1907 in Paul Ehrlich's lab by Alfred Bertheim. [4] The antisyphilitic activity of this compound was discovered by Sahachiro Hata in 1909, during a survey of hundreds of newly synthesized organic arsenical compounds. Ehrlich had theorized that by ...
In 1909, Sahachiro Hata went to work in Paul Ehrlich's laboratory, the National Institute for Experimental Therapeutics, in Frankfurt, Germany to help Ehrlich in his quest to develop a treatment for syphilis called the 'magic bullet.' [4] The causative agent of syphilis was discovered to be the spirochete Treponema pallidum by Fritz Schaudinn ...
The first effective treatment for a sexually transmitted infection was salvarsan, a treatment for syphilis. With the discovery of antibiotics , a large number of sexually transmitted infections became easily curable, and this, combined with effective public health campaigns against STIs, led to a public perception during the 1960s and 1970s ...
In 1905 Schaudinn and Hoffmann discovered the bacterium that was responsible for syphilis, a spiral-shaped spirochete called Treponema pallidum, which they first called Spirochaeta pallida. [1] [2] The organism was removed from a papule in the vulva of a woman with secondary syphilis.