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  2. Mechanism of action - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action

    Common examples of drugs that work in this way are antacids and laxatives. [2] In contrast, a mode of action (MoA) describes functional or anatomical changes, at the cellular level, resulting from the exposure of a living organism to a substance.

  3. Mode of action - Wikipedia

    en.wikipedia.org/wiki/Mode_of_action

    A mechanism of action of a chemical could be "binding to DNA" while its broader mode of action would be "transcriptional regulation". [3] However, there is no clear consensus and the term mode of action is also often used, especially in the study of pesticides, to describe molecular mechanisms such as action on specific nuclear receptors or ...

  4. Monoamine oxidase - Wikipedia

    en.wikipedia.org/wiki/Monoamine_oxidase

    The suggested mechanism for this effect is the decreased ability of those with low MAO-A activity to quickly degrade norepinephrine, the synaptic neurotransmitter involved in sympathetic arousal and rage. This is argued to provide direct support for the idea that genetic susceptibility to disease is not determined at birth, but varies with ...

  5. Biological functions of nitric oxide - Wikipedia

    en.wikipedia.org/wiki/Biological_functions_of...

    Biological functions of nitric oxide are roles that nitric oxide plays within biology. Nitric oxide (nitrogen monoxide) is a molecule and chemical compound with chemical formula of N O . In mammals including humans, nitric oxide is a signaling molecule involved in several physiological and pathological processes. [ 1 ]

  6. Acetylcholinesterase - Wikipedia

    en.wikipedia.org/wiki/Acetylcholinesterase

    AChe mechanism of action [5]. AChE is a hydrolase that hydrolyzes choline esters. It has a very high catalytic activity—each molecule of AChE degrades about 5,000 molecules of acetylcholine (ACh) per second, [6] approaching the limit allowed by diffusion of the substrate.

  7. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    The underlying mechanism for the deleterious effect proposes that endothelial cells lining the microvasculature in the body express COX-2, whose selective inhibition results in levels of prostaglandin I2 (PGI2, prostacyclin) down-regulated relative to thromboxane (since COX-1 in platelets is unaffected).

  8. Mechanism (biology) - Wikipedia

    en.wikipedia.org/wiki/Mechanism_(biology)

    In biology, a mechanism is a system of causally interacting parts and processes that produce one or more effects. [1] Phenomena can be explained by describing their mechanisms. For example, natural selection is a mechanism of evolution ; other mechanisms of evolution include genetic drift , mutation , and gene flow .

  9. Biological target - Wikipedia

    en.wikipedia.org/wiki/Biological_target

    Examples of common classes of biological targets are proteins and nucleic acids. The definition is context-dependent, and can refer to the biological target of a pharmacologically active drug compound , the receptor target of a hormone (like insulin ), or some other target of an external stimulus.