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Quinine is a medication used to treat malaria and babesiosis. [5] ... mauveine, was discovered by William Henry Perkin in 1856 while he was attempting to synthesize ...
Quinine sulfate later proved to be an important remedy for the disease malaria. Quinine is the active anti-malarial ingredient in the bark of cinchona tree. [1] [2] Neither of the partners chose to patent their discovery of this compound, releasing it for everybody to use. In 1823 they discovered nitrogen in alkaloid compounds.
William Perkin continued active research in organic chemistry for the rest of his life: he discovered and marketed other synthetic dyes, including Britannia Violet and Perkin's Green; he discovered ways to make coumarin, one of the first synthetic raw materials of perfume, and cinnamic acid.
In 1867 he discovered that quinine was highly toxic to micro-organisms in impure water, [2] and demonstrated that quinine hydrochlorate with neutral or slightly basic reaction was an effective poison for the protoplasms of decomposing plants and impeded many fermenting and putrid processes. [3]
Letter from Perkin's son, with a sample of dyed silk. Mauveine, also known as aniline purple and Perkin's mauve, was one of the first synthetic dyes. [1] [2] It was discovered serendipitously by William Henry Perkin in 1856 while he was attempting to synthesise the phytochemical quinine for the treatment of malaria. [3]
A significant contribution to the chemistry of alkaloids in the early years of its development was made by the French researchers Pierre Joseph Pelletier and Joseph Bienaimé Caventou, who discovered quinine (1820) and strychnine (1818).
The following is a table of drugs organized by their year of discovery. Naturally occurring chemicals in plants, including alkaloids, have been used since pre-history.In the modern era, plant-based drugs have been isolated, purified and synthesised anew.
Jesuit's bark, also known as cinchona bark, Peruvian bark or China bark, is a former remedy for malaria, as the bark contains quinine used to treat the disease. [1] The bark of several species of the genus Cinchona , family Rubiaceae indigenous to the western Andes of South America, was introduced to Jesuit missionaries during the 17th century ...