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Glutathione (GSH, / ˌ ɡ l uː t ə ˈ θ aɪ oʊ n /) is an organic compound with the chemical formula HOCOCH(NH 2)CH 2 CH 2 CONHCH(CH 2 SH)CONHCH 2 COOH. It is an antioxidant in plants , animals , fungi , and some bacteria and archaea .
A suppository is a dosage form used to deliver medications by insertion into a body orifice (any opening in the body), where it dissolves or melts to exert local or systemic effects. There are three types of suppositories, each to insert into a different sections: rectal suppositories into the rectum , vaginal suppositories into the vagina ...
Historical packaging of Anusol suppositories. Anusol (also AnuSol) is a brand of medications that can be used to treat hemorrhoids. The Anusol range includes creams, ointments, and suppositories. Anusol is now known under the brand name Tucks in the United States and some other areas, while being marketed under the Anusol name in other markets ...
Preparation H is an American brand of medications that is made by Pfizer, used in the treatment of hemorrhoids.Hemorrhoids are caused at least in part by inflamed blood vessels, and most versions of Preparation H work by reducing inflammation in blood vessels.
A rudimentary form of "dry" enema is the use of a non-medicated glycerin suppository. [1] However, due to the relative hardness of the suppository – necessary for its insertion into the human body – before glycerin can act, it must be melted by the heat of the body, and hence it does not take effect for up to an hour.
In subsequent phase II reactions, these activated metabolites are conjugated with charged species such as glutathione, sulfate, glycine or glucuronic acid. These reactions are catalysed by a large group of broad-specificity transferases. UGT1A6 is a human gene encoding a phenol UDP glucuronosyltransferase active on simple phenols. [106]
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