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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
Side effects of estradiol undecylate versus cyproterone acetate in men Side effect Estradiol undecylate 100 mg/month i.m. (n = 96) Cyproterone acetate 100 mg/day oral (n = 95) n % n % Gynecomastia* 74: 77.1%: 12: 12.6% Breast tenderness* 84: 87.5%: 6: 6.3% Sexual impotence
Side effects of cyproterone acetate; Template:Side effects of cyproterone acetate in the SExual-HOrmonal Surveillance STudy (SEHOST) Template:Side effects of estradiol undecylate versus cyproterone acetate in men; Template:Side effects of estrogen plus high- versus low-dose cyproterone acetate in women
[1] [7] Cyproterone acetate acts both directly as an antiandrogen in prostate cancer cells and also functions to indirectly decrease serum testosterone levels. The latter causes the limitations of cyproterone acetate, which are central effects on androgen secretion, with subsequent loss of libido and sexual potency.
Cyproterone is a potent antiandrogen, similarly to CPA. [5] [6] However, it has approximately three-fold lower potency as an antagonist of the androgen receptor (AR) relative to CPA. [6] Like CPA, cyproterone is actually a weak partial agonist of the AR, and hence has the potential for both antiandrogenic and androgenic activity in some ...
But some research has noted rare but serious side effects of once-weekly, 2.4-milligram (mg) semaglutide injections, such as pancreatitis, acute kidney injury, gallbladder issues, and thyroid cancer.
This template can be used to easily insert a table detailing the side effects of estrogen plus high- versus low-dose cyproterone acetate in women into an article. It comes with five pre-provided references. By passing the parameter |state=mw-collapsed, the table can be displayed as collapsed by default.