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In medicine these proteins are useful and are used as a mitogen to trigger T-lymphocyte cell division and to activate latent HIV-1 from human peripheral lymphocytes.In neuroscience, anterograde tracing is a research method that uses the protein product phytohaemagglutinin PHA-L as a molecular tracer that can be taken up by the cell and transported across the synapse into the next cell thereby ...
Illustration showing influenza virus attaching to cell membrane via the surface protein hemagglutinin. Hemagglutinins (alternatively spelt haemagglutinin, from the Greek haima, 'blood' + Latin gluten, 'glue') are homotrimeric glycoproteins present on the protein capsids of viruses in the Paramyxoviridae and Orthomyxoviridae families.
Stillmark isolated ricin, an extremely toxic hemagglutinin, from seeds of the castor plant (Ricinus communis). The first lectin to be purified on a large scale and available on a commercial basis was concanavalin A, which is now the most-used lectin for characterization and purification of sugar-containing molecules and cellular structures. [36]
23845 Ensembl ENSG00000258227 ENSMUSG00000029915 UniProt Q9NY25 Q9R007 RefSeq (mRNA) NM_001301167 NM_013252 NM_001038604 NM_021364 RefSeq (protein) NP_001288096 NP_037384 NP_001033693 NP_067339 Location (UCSC) Chr 7: 141.93 – 141.95 Mb Chr 6: 40.55 – 40.56 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse C-type lectin domain family 5 member A (CLEC5A), also known as C-type lectin ...
Soybean agglutinins (SBA) also known as soy bean lectins (SBL) are lectins found in soybeans. It is a family of similar legume lectins. As a lectin, it is an antinutrient that chelates minerals. In human foodstuffs, less than half of this lectin is deactivated even with extensive cooking (boiling for 20 minutes). [1]
Collectin MBL is involved in activation of the lectin complement pathway. [32] [33] There are three serine proteases, MASP-1, 2 and 3 (MBL-associated serine proteases), which participate in activation of the lectin pathway. MASP-2 has a cleavage activity and it is essential for forming lectin C3 and C5 convertases and for activation of the ...
Nutritionists Robin DeCicco of the New York area and Ilana Muhlstein of Los Angeles shared nutritious alternatives to typical Valentine's Day sweets such as chocolate, gummy candies and baked goods.
All three known members of the selectin family (L-, E-, and P-selectin) share a similar cassette structure: an N-terminal, calcium-dependent lectin domain, an epidermal growth factor (EGF)-like domain, a variable number of consensus repeat units (2, 6, and 9 for L-, E-, and P-selectin, respectively), a transmembrane domain (TM) and an intracellular cytoplasmic tail (cyto).