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Cutibacterium acnes bacteria predominantly live deep within follicles and pores, although they are also found on the surface of healthy skin. [3] In these follicles, C. acnes bacteria use sebum, cellular debris and metabolic byproducts from the surrounding skin tissue as their primary sources of energy and nutrients.
The most studied of these infections is acne vulgaris, caused by Cutibacterium acnes (formerly Propionibacterium acnes). [9] It is a chronic inflammatory disease caused by the blockage of pilosebaceous units causing inflammatory lesions, non-inflammatory lesions or a mixture of both on the face, neck and/or chest.
Moreover, S. epidermidis biofilm formation by releasing the exopolysaccharide intercellular adhesion (PIA) provides the susceptible anaerobic environment to P. acnes colonisation and protects it from the innate human immunity molecules. [23] Both P. acnes and S. epidermidis can interact to protect the host skin health from pathogens ...
Overview. Acne is a skin condition characterized by clogged pores. When pores get clogged, it causes red lesions — which you know as pimples — to form on the face or other areas of the body ...
Propionibacterium acnes type zappae is a gram-positive, anaerobic, and endophytic bacterium species of Propionibacterium. In 2014, it was found in an interkingdom bacterial transfer with grapevines ( Vitis vinifera ), which is unexpected because P. acne is found on human skin. [ 1 ]
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The relative population of C. acnes is similar between those with acne and those without. [39] [40] Current treatment includes topical and systemic antibacterial drugs which result in decreased C. acnes colonisation and/or activity. [41] Potential probiotic treatment includes the use of Staphylococcus epidermidis to inhibit C. acnes growth.
Up to 57% of P. acnes strains developed resistance to doxycycline. [38] When bacteriologic testing indicates appropriate susceptibility to the drug, doxycycline may be used to treat these infections caused by Gram-positive bacteria: [29] [30] upper respiratory infections caused by Streptococcus pneumoniae (formerly Diplococcus pneumoniae), [29 ...