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Psilocybin is itself biologically inactive but is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of other classical psychedelics. Effects include euphoria , hallucinations , changes in perception , a distorted sense of time , [ 19 ] and perceived spiritual experiences .
However, tolerance to psilocybin is a well understood concept, with repeatedly higher doses being needed in order to achieve the same effect, due to the down regulation of 5HT2A receptors. [6] There is also documented cross-tolerance between psilocybin and LSD, meaning that a higher dose of these substances is needed to get the same effect when ...
In 2007, a paper by Redhead et al. proposed conserving the genus Psilocybe with Psilocybe semilanceata as its type species. [5] The suggestion was accepted by unanimous vote of the Nomenclature Committee for Fungi of the International Botanical Congress in 2010, meaning that P. semilanceata (a member of the bluing clade) now serves as the type species of the genus. [6]
Psilocybe semilanceata, commonly known as the liberty cap, is a species of fungus which produces the psychoactive compounds psilocybin, psilocin and baeocystin.It is both one of the most widely distributed psilocybin mushrooms in nature, and one of the most potent.
[30] [31] Besides psilocin, norpsilocin, baeocystin, norbaeocystin, and aeruginascin may also be present, which might result in an entourage effect and modify the effects of magic mushrooms. [ 24 ] [ 28 ] Panaeolus subbalteatus , one species of magic mushroom, had the highest amount of psilocybin compared to the rest of the fruiting body. [ 28 ]
Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C. indica. The medicinal effects of cannabis are widely studied, and are active topics of research both at universities and private research ...
Psilocybe cubensis, commonly known as the magic mushroom, shroom, golden halo, golden teacher, cube, or gold cap, is a species of psilocybin mushroom of moderate potency whose principal active compounds are psilocybin and psilocin.
Ibotenic acid or (S)-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid, also referred to as ibotenate, is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere.