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  2. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.

  3. EC50 - Wikipedia

    en.wikipedia.org/wiki/EC50

    Half maximal effective concentration (EC 50) is a measure of the concentration of a drug, antibody or toxicant which induces a biological response halfway between the baseline and maximum after a specified exposure time. [1] More simply, EC 50 can be defined as the concentration required to obtain a 50% [...] effect [2] and may be also written ...

  4. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    It is possible to calculate the amount of a drug in the blood plasma that has a real potential to bring about its effect using the formula: D e = B ⋅ D a {\displaystyle De=B\cdot Da\,} where De is the effective dose , B bioavailability and Da the administered dose.

  5. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level , but this also means that, without an initial higher dose, it would take a long ...

  6. Driving into Manhattan? That’ll cost you, as new congestion ...

    www.aol.com/driving-manhattan-ll-cost-congestion...

    New York’s new toll for drivers entering the center of Manhattan debuted Sunday, meaning many people will pay $9 to access the busiest part of the Big Apple during peak hours.

  7. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    Polonium in the body has a biological half-life of about 30 to 50 days. Caesium in the body has a biological half-life of about one to four months. Mercury (as methylmercury) in the body has a half-life of about 65 days. Lead in the blood has a half life of 28–36 days. [29] [30] Lead in bone has a biological half-life of about ten years.

  8. Up To 40 Percent Of Women Don't Need Antibiotics To Clear Up ...

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  9. Would you drink hot chocolate with bone broth in it?

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    Wellness influencers on TikTok and Instagram are touting bone broth hot chocolate as a nutritional alternative to the regular winter beverage.

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