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Shingles, also known as herpes zoster or zona, [6] is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [7] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1]
Shingles vaccination is the only way for adults to be protected against both shingles and postherpetic neuralgia, with two vaccines approved for use in people over age 50. [3] The zoster vaccine Shingrix provides around 90% protection from postherpetic neuralgia, and has been used in many countries since 2017.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Shingles, also called zoster or herpes zoster, is a viral infection that affects the nerves.
Aciclovir has a high distribution rate; protein binding is reported to range from 9 to 33%. [49] The elimination half-life (t 1/2) of aciclovir depends according to age group; neonates have a t 1/2 of 4 hours, children 1–12 years have a t 1/2 of 2–3 hours whereas adults have a t 1/2 of 3 hours. [3]
Famciclovir is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is a prodrug form of penciclovir with improved oral bioavailability. Famciclovir is marketed under the trade name Famvir .
It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children. As a late complication of VZV infection, Ramsay Hunt syndrome type 2 may develop in rare cases. VZV infections are species-specific to humans. The virus can survive in external environments for a few hours.
Morgellons (/ m ɔːr ˈ ɡ ɛ l ə n z /) is the informal name of a self-diagnosed, scientifically unsubstantiated skin condition in which individuals have sores that they believe contain fibrous material.