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  2. Hemoglobin C - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_C

    Overall, hemoglobin C disease is one of the more benign hemoglobinopathies. [6] Mild-to-moderate reduction in RBC lifespan may accompany from mild hemolytic anemia. Individuals with hemoglobin C disease have sporadic episodes of musculoskeletal (joint) pain. [6] People with hemoglobin C disease can expect to lead a normal life. [14]

  3. Thalassemia - Wikipedia

    en.wikipedia.org/wiki/Thalassemia

    Hemoglobin is a protein containing iron that facilitates the transportation of oxygen in red blood cells. [30] Hemoglobin in the blood carries oxygen from the lungs to the other tissues of the body, where it releases the oxygen to enable metabolism. A healthy level of hemoglobin for men is between 13.2 and 16.6 grams per deciliter, and in women ...

  4. Hemoglobinopathy - Wikipedia

    en.wikipedia.org/wiki/Hemoglobinopathy

    Unstable hemoglobin variants are mutations that cause the hemoglobin molecule to precipitate, spontaneously or upon oxidative stress, resulting in hemolytic anemia. Precipitated, denatured hemoglobin can attach to the inner layer of the plasma membrane of the red blood cell (RBC) forming Heinz bodies , leading to premature destruction of the ...

  5. Management of thalassemia - Wikipedia

    en.wikipedia.org/wiki/Management_of_thalassemia

    Patients with β-thalassemia trait should be warned that their condition can be misdiagnosed for the common Iron deficiency anemia. They should eschew empirical use of Iron therapy; yet iron deficiency can develop during pregnancy or from chronic bleeding. [3]

  6. Microcytic anemia - Wikipedia

    en.wikipedia.org/wiki/Microcytic_anemia

    Microcytic anaemia; Microcytosis is the presence of red cells that are smaller than normal. Normal adult red cell has a diameter of 7.2 µm. Microcytes are common seen in with hypochromia in iron-deficiency anaemia, thalassaemia trait, congenital sideroblastic anaemia and sometimes in anaemia of chronic diseases.

  7. Beta thalassemia - Wikipedia

    en.wikipedia.org/wiki/Beta_thalassemia

    Long-term transfusion therapy (in those with transfusion dependent beta thalassemia) is a treatment used to maintain hemoglobin levels at a target pre-transfusion hemoglobin level of 9–10.5 g/dL (11–12 g/dL in those with concomitant heart disease). [8] To ensure quality blood transfusions, the packed red blood cells should be leucoreduced.

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