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Flu vaccines are contraindicated for people who have experienced a severe allergic reaction in response to a flu vaccine or to any component of the vaccine. LAIVs are not given to children or adolescents with severe immunodeficiency or to those who are using salicylate treatments because of the risk of developing Reye syndrome . [ 96 ]
To produce viral vaccines, candidate vaccine viruses are grown in mammalian, avian or insect tissue culture of cells with a finite lifespan. [5] These cells are typically Madin-Darby Canine Kidney cells, [6] but others are also used including monkey cell lines pMK and Vero and human cell lines HEK 293, MRC 5, Per.C6, PMK, and WI-38. [7]
Polyvalent influenza vaccine is a type of influenza vaccine that provides immunity against more than one type of antigen. [1] In the second week after receiving the flu shot, the body's immune system is triggered by the antigens so the body starts producing antibodies. These antibodies help fight against influenza viruses.
Influenza viruses cause billions of flu infections and thousands of deaths across the globe each year. Developing an effective, long-term flu vaccine is challenging because of viral mutations.
A vaccine that contains the A/Vietnam/1194/2004 (H5N1) flu strain. [28] Pumarix: A vaccine approved for medical use in the European Union in March 2011. [29] Seqirus/Audenz: A vaccine for adults that contains a killed flu strain called A/Astrakhan/3212/2020 (H5N8)-like strain. [30] Some older H5N1 vaccines for humans that have been licensed are:
In the early days of vaccine manufacture, significant variations in the efficacy of different batches of the same vaccine were correctly assumed to be caused by contamination of the reaction vessels. However, it was soon found that more scrupulous cleaning actually seemed to reduce the effectiveness of the vaccines, and some contaminants ...
Protein anabolism is the process by which proteins are formed from amino acids. It relies on five processes: amino acid synthesis, transcription , translation , post translational modifications , and protein folding .
Adults 65 years of age and older can have a weaker immune response to flu vaccines, making them more likely to get sick with the flu or get flu complications even when vaccinated, according to the ...
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