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Cell nuclei stained blue. Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942. [1][2][3] The Papanicolaou stain is one of the most widely used stains in cytology, [1] where it is used to aid pathologists in making a diagnosis.
Pap test. The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and ...
Cytopathology (from Greek κύτος, kytos, "a hollow"; [1] πάθος, pathos, "fate, harm"; and -λογία, -logia) is a branch of pathology that studies and diagnoses diseases on the cellular level. The discipline was founded by George Nicolas Papanicolaou in 1928. Cytopathology is generally used on samples of free cells or tissue ...
Diff-Quik is a commercial Romanowsky stain variant used to rapidly stain and differentiate a variety of pathology specimens. It is most frequently used for blood films and cytopathological smears, including fine needle aspirates. [1][2][3] The Diff-Quik procedure is based on a modification of the Wright-Giemsa stain pioneered by Harleco in the ...
It is a component of Papanicolaou stains together with eosin Y and bismarck brown Y. [1] In pap smears, Light Green SF confers a blue staining for the cytoplasm of active cells such as columnar cells, parabasal squamous cells, and intermediate squamous cells. [3] It usually comes as a disodium salt. Its maximum absorption is at 630 (422) nm.
Koilocyte. ThinPrep pap smear with group of normal cervical cells on left and HPV -infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human ...
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