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Frailty can have various symptoms including muscle weakness (reduced grip strength), slower walking speed, exhaustion, unintentional weight loss, and frequent falls. [ 3 ] [ 4 ] Older people with certain medical conditions such as diabetes , heart disease and dementia , are also more likely to have frailty.
Constitutional Symptoms. Unexplained weight loss: Weight loss that is unintended and not explained by diet, exercise or other illness may be a warning sign of many types of cancer; Unexplained pain: Pain that persists, has no clear cause, and does not respond to treatment may be a warning sign of many types of cancers.
Unwanted weight loss of more than 5% within 6 months. [2] [19] For people with a BMI of less than 20kg/m 2, weight loss of more than 2%. [2] [19] [27] For people with sarcopenia, weight loss of more than 2%. [2] [19] [27] New ways to score and stage cachexia are being explored, particularly in people with advanced cancer. [19]
Graves disease develops in about 0.5% of males and 3.0% of females. [5] It occurs about 7.5 times more often in women than in men. [1] Often, it starts between the ages of 40 and 60, but can begin at any age. [6] It is the most common cause of hyperthyroidism in the United States (about 50 to 80% of cases).
Experts say that recent, unexplained weight loss is a "well-known phenomenon" associated with cancer. But other health conditions can cause weight loss as well.
As such it is recognised that the boundary defining symptoms as medically unexplained is increasingly becoming blurred. [8] Women are significantly more likely than men to be diagnosed with Medically Unexplained Symptoms. [9] [10] Childhood adversity and/or abuse, and the death or serious illness of a close family member are significant risk ...
Other common leukemia symptoms include fatigue, frequent infections, shortness of breath, pale skin, unexplained weight loss, pain or tenderness in your bones or joints, pain under your ribs on ...
Symptoms of the condition in males consist of loss of libido, impotence, infertility, shrinkage of the testicles, penis, and prostate, diminished masculinization (e.g., decreased facial and body hair growth), low muscle mass, anxiety, depression, fatigue, vasomotor symptoms (hot flashes), insomnia, headaches, cardiomyopathy and osteoporosis.