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Aldosterone is the primary of several endogenous members of the class of mineralocorticoids in humans. [citation needed] Deoxycorticosterone is another important member of this class. Aldosterone tends to promote Na + and water retention, and lower plasma K + concentration by the following mechanisms:
Radiation damage event. Interaction of an energetic incident particle with a lattice atom. Transfer of kinetic energy to the lattice atom, giving birth to a primary displacement atom. Displacement of the atom from its lattice site. Movement of the atom through the lattice, creating additional displaced atoms.
Nuclear physics. Radioactive decay (also known as nuclear decay, radioactivity, radioactive disintegration, or nuclear disintegration) is the process by which an unstable atomic nucleus loses energy by radiation. A material containing unstable nuclei is considered radioactive. Three of the most common types of decay are alpha, beta, and gamma ...
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2. [5] MR is a receptor with equal affinity for mineralocorticoids and glucocorticoids.
With larger weapons, above 50 kt (200 TJ), blast and thermal effects are so much greater in importance that prompt radiation effects can be ignored. The neutron radiation serves to transmute the surrounding matter, often rendering it radioactive. When added to the dust of radioactive material released by the bomb, a large amount of radioactive ...
Hyperaldosteronism. Hyperaldosteronism is a medical condition wherein too much aldosterone is produced. High aldosterone levels can lead to lowered levels of potassium in the blood (hypokalemia) and increased hydrogen ion excretion (alkalosis). Aldosterone is normally produced in the adrenal glands. Primary aldosteronism is when the adrenal ...
Cancer induction. Cancer induction is the most significant long-term risk of exposure to a nuclear bomb. Approximately 1 out of every 80 people exposed to 1 Gray will die from cancer, in addition to the normal rate of 20 out of 80. About 1 in 40 people will get cancer, in addition to the typical rates of 16-20 out of 40.
There are 2 common ways to treat adrenalism with radiation, namely conventional external beam or stereotactic radiosurgery. The former administers a high dose of radiation around the gland aiming to destroy or reduce the size of the tumor or kill the cell directly by inhibiting cellular proliferation of the cells through exposure to radiation ...